HORDB

ID: hor002569
Uniprot ID: A0A2S1VVM5
Protein name: As-NLP-23-2
Gene name: nlp-2
Organism: Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Family: NA
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ascaris (genus), Ascarididae (family), Ascaridoidea (superfamily), Ascaridomorpha (infraorder), Spirurina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: SLALGRVDFRPG
Length: 12
Propeptide: MHAKLAALFPLLVVSTLSLAEEERRAKRSIVIGRGIYRPTNWEAISESEFPAELQKRSMALGRLAFRPGKRSLALGRVDFRPGKRNVDIADKDIEYLMEDSMGKRSAAFGRFHFRPGKRSLALGRSGFRPGKRSLALGRVGFRPGKRASGEVLIDPCSIEIDSLWGDMYDIAQLYEEISKNCGKV
Signal peptide: MHAKLAALFPLLVVSTLSLA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002569_AF2.pdb

hor002569_ESM.pdb

Mass:	148387	Formula:	C57H94N18O16
Absent amino acids:	CEHIKMNQTWY	Common amino acids:	GLR
pI:	10.4	Basic residues:	2
Polar residues:	3	Hydrophobic residues:	5
Hydrophobicity:	5.83	Boman Index:	-2141
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	97.5
Instability Index:	640.83	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 21524146
Title: Discovery of Neuropeptides in the Nematode Ascaris Suum by Database Mining and Tandem Mass Spectrometry